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Tiny Khloe: 2026 Exxxotica Interview| Author | Post |
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| jim2 Member 232 Posts 7/06 |  Posted - Nov 6 2013 : 5:54PMMy doc wants to put me on a drug that he thinks will help me sleep better. It's not any of the brand names we frequently hear about. After looking at the side-effects I noticed the warning about the rare but serious side effect known as Priapism. I learned Priapism is the term for having a hard-on that doesn't go away. It's what Viagra users are warned about on TV. In the case of Viagra however, most users typically have dead wood issues so taking Viagra probably won't have that kind of reaction. In my case however I never have a problem with getting it up, so I'm concerned that taking it may keep me up permanently. About 1 in 6000 users develop it. The doc says he never had anyone get that symptom. I heard if you do get it you must go to hospital where they stick needles in your dick, or perhaps do surgery. I want to get a good night of sleep, but I don't want to risk ruining my dick permanently. Would you try this or insist on another med? [Link] |
Hardware  All-Star Member Your other left 14595 Posts 3/02 | Posted - Nov 6 2013 : 6:42PM [Link] |
| BYOB_Kenobi Senior Member “Life can only be understood backwards; but it must be lived forwards.” - Kierkegaard 2684 Posts 8/09 | Posted - Nov 7 2013 : 10:37PM There is always risks when putting anything in your body, esp medication (or even food/water). Too high dosage, allergic reactions, side effects, costs, etc. etc. therefore medication usually is always a cost-benefit analysis. But many medications have/are beneficial too and have helped billions. That said, you need to figure out how bad your sleeping problem is (is it affecting your daily life, cognition, career, relationship). But there are always other options too. I know of many sleeping aids to help that don't have risk of permanent priapism. There's also non-medical therapies (I have to say for me personally, any drug that has known permanent side effects anything but rare (lot higher than 1:6,000), I try and stay away from, but this is my personal opinion). I personally use plant based Melatonin (0.5mg per night) and found this one of the most effective after many different sleeping medications and non-medical treatments. Just remember it's your body, and don't let a doctor prescription/medication preferences intimidate you to asking for alternatives. A sign of a good doctor is one who will offer options and not just say take/try this. [Link] |
| Hardware All-Star Member Your other left 14595 Posts 3/02 | Posted - Nov 8 2013 : 1:19AM One other thing, it might help you sleep better to challenge your brain more during the day. [Link] |
| Kimi Lixx Senior Member 2012 Posts 6/01 | Posted - Nov 8 2013 : 9:01AM It fixes the problem, though. I'll be wakeful and alert enough to handle the rest of the day on 4 hours of good sleep, and then I'll easily fall asleep that night without assistance and be back on my normal sleep schedule. [Link] |
| jim2 Member 232 Posts 7/06 | Posted - Nov 8 2013 : 10:16AM [Link] |
| BYOB_Kenobi Senior Member “Life can only be understood backwards; but it must be lived forwards.” - Kierkegaard 2684 Posts 8/09 | Posted - Nov 9 2013 : 3:36AM Click to expand Also another thing the vast majority of people aren't aware of (Kimi, I hope you don't use this). My endocrinology professor was awesome and made us learn everything (it was a grad class) - half lives, WNL, binding proteins, physiology, etc. etc. She also gave us real life applications and tips/secrets that never heard from anywhere else. She said there are two types/sources of melatonin supplements - 1 is from animals and the other is plant based. Melatonin from am animal source are typically extracts of bovine pineal gland. As you know, Mad Cow/BSE is caused by prions and we still don't know anything about prions and they are scary as fuck to the biological/medical community. Therefore, common sense dictates people should steer away from animal based melatonin. If the label doesn't explicitly say plant derived/source, then it could be bovine and should look with explicit labeling of plant based. That's last thing our public needs is taking bovine extract/tissue since the age of BSE infections and we know it effects brain tissue and prions are responsible. I started on 0.33 qd, but didn't do anything and upped it to 0.5mg qd and found it enough. More than that had trouble/hangover effect next morning. Also remember the pathway for metabolism of melatonin relies on serotonin (serotonin/5-HT gets biotransformed to melatonin). So any meds altering serotonin levels could affect circulating levels of melatonin prior to introducing any exogenous melatonin.  Trazadone is (or used to be, not sure if they got approval for indication for insomnia) an antidepressant and studies and clinicians noticed a common side effect was drowsiness and inducing sleep, so since this discovery, doctors prescribe this off-label (like many other drugs) for insomnia or sleep problems, especially with new anti-benzodiazepine prescribing trend.I know a lot of people personally who have take Trazadone (many doctors now use it as 1st-line treatment) and many say has worked getting them to sleep, but caused major hangover effect the next day and function horribly (cognitively), similar to Benadryl/Diphenhydramine. There's other options besides other treatment options too, there's second opinions. I've had to see get 2nd/3rd opinions, before I found a good doc or one that treated several of my medical conditions effectively. So don't rule that out (I'm not saying you should either way, but it's always an option). [Link] |
| Kimi Lixx Senior Member 2012 Posts 6/01 | Posted - Nov 9 2013 : 11:33AM I started on a single tablet dosage(3 mg), but that didn't seem to have any effect at all. Two tablets definitely helps me fall asleep. I have not tried 3 tablets (or less than 1 whole tablet), and I have not tried a second dosage on mid-night waking. I think that will be my next variation. Since it doesn't seem to have any sort of "hang-over" or groggy effect on me I doubt that, even if it doesn't induce sleeping, it will cause any further disruption. [Link] |
| mharris127 Senior Member 1844 Posts 8/09 | Posted - Nov 10 2013 : 3:55AM A couple of notes for those looking for a sleeping medication. Some doctors (mainly older docs that were trained before the side effects were well known) will prescribe anti psychotic medication (Haldol, Thorazine, Zyprexa, Abilify, Risperdal, etc.) in low doses to those that need a strong sleeping pill. For those without an appropriate mental illness (usually schizophrenia or bipolar I disorder, they are sometimes also used for behavior control in autistic children) that actually needs such medication that is dangerous and obnoxious. One, you can get psuedo-parkinsonism and tardive dyskinesia from them and anyone that knows what those terms are knows they aren't something to fuck with. Two, many work for 24 hours plus so you may spend the next day sleeping at your work desk. For those with an appropriate mental illness these medications are a Godsend but unless you (or anyone else) need them to stay out of the mental hospital or jail/juvenile please don't go this route just to get to sleep at night. The other note is regarding benzodiazepines such as Valium, Xanax, Klonopin and Librium. They work well for temporary issues regarding sleep such as bereavement but should usually only be used for 14 days or less at a time with at least a month's break between courses as they are addictive and if you take them too long and suddenly stop you are almost guaranteed to have seizures (I have an epileptic in-law, don't tempt fate here -- her life is not fun). They are also used for mental illnesses and epilepsy for years at a time, addiction is less of a concern if the med keeps you out of the mental hospital or ICU. If you are on one of these meds for something other than sleep or transient anxiety or have been on them for more than about 15 days please don't stop taking them without medical advice. If you have made the mistake of taking benzos long-term for sleep purposes your doc can slowly withdraw you from them (over a period of a couple of months in some cases) in order to avoid seizures. Jim, if you are comfortable doing so you may PM me and I would be happy to look up whatever drug your doc is attempting to prescribe to you or you can do so yourself on www.webmd.com or www.pdrhealth.com anonymously by either brand or generic name. [Link] |
| jim2 Member 232 Posts 7/06 | Posted - Nov 10 2013 : 10:30AM Trazodone and Priapism [Link] |
| BYOB_Kenobi Senior Member “Life can only be understood backwards; but it must be lived forwards.” - Kierkegaard 2684 Posts 8/09 | Posted - Nov 10 2013 : 12:14PM 1st gen psychotic and bipolar meds was extremely toxic and had horrible side effects. These 2nd generation meds lessened some of these side effects but added new ones. Many antipsychotics and bipolar (1st and 2nd gen) have side effects of blood disorders. Out of all side effect profiles, blood disorders are extreme dangerous (mess with white blood cell counts like lowing white counts causing immunosuppression). Seroquel in on rise for sleep use, but not only has shown side effects of causing blood disorders, but also cardiovascular effects (QT interval and cholesterol). Just look at drug box warnings for these. And then there's the pseudo-parkinson and TD side effects which affect Extrapyramidal System (EPS) and so common there's a new diagnosis for people who uses these drugs and develop NMS (Neuroleptic malignant syndrome). Doctors/clinicians should not be prescribing any psychotics/bipolar meds for sleeping. These family/classes of drugs are nasty and only should be used for patients with schizophrenia or bipolar disorder, but both PCPs and specialists are prescribing these for sleep at alarming rates, leveraging their sedating effects. It's gotten so bad that doctors (both PCPs adn specialists) are prescribing antipsychotics to kids/teens with only behavioral problems (no signs of psychosis or even workups), which is highly unethical and goes directly against the Hippocratic Oath, but this is another thread. [Link] |
| BYOB_Kenobi Senior Member “Life can only be understood backwards; but it must be lived forwards.” - Kierkegaard 2684 Posts 8/09 | Posted - Nov 10 2013 : 12:14PM [Link] |
| Hardware All-Star Member Your other left 14595 Posts 3/02 | Posted - Nov 10 2013 : 4:07PM [Link] |
| BYOB_Kenobi Senior Member “Life can only be understood backwards; but it must be lived forwards.” - Kierkegaard 2684 Posts 8/09 | Posted - Nov 10 2013 : 5:47PM He's a good story to illustrate this. As a kid/young teen. I had to have massive reconstructive surgery, so my mom go me to see a specialist at the best pediatric hospital in the country/world. She also got me in with the best pediatric orthopedic surgeon (nurses and doctors always remarked if they had a need, there's no better surgeon in the country and would see my surgeon). Had many pre-op checkups, surgical planning, and peri-operative anesthesia, etc. etc. appointments and my mom knew all my medical history and drug allergies to heart and always stated them even if not asked. She routinely said I had history of multiple allergic reactions to clindamycin including anaphylaxis. She even told the doctor in the pre-op waiting room before going into OR (for the dozenth time). Surgery was done (came out spectacular and non-affiliated docs commented excellent job). Finally get released and she prescribes on paper an antibiotic. My mom fills it and I take it and soon start having problems breathing. It was clindamycin. Went into anaphylactic shock and O2 sat dropped to 70% by time got to ED. Finally got the chart and notes for followup and found it was written everywhere. One of the best doctors on earth, one of the best hospitals on earth, good pharmacy and still had preventable allergic reaction (easily could have died) and it told at least 10-20 times prior to surgery to my surgical team during pre-op appts and it fell thru the cracks. Furthermore, it's a common check and procedure. When they say prescribing and filling prescription errors kills, what 10,000s to 100,000s patients a year, they aren't kidding. It seems abstract but your cousin and my experience was simply been part of that statistic. It's especially f-ing pathetic considering our amount of money we pay for heatlh care and prescriptions and have the best medical schools in the world, but kill patients no on the table but by one word (drug name) or 1 or 2 numbers (dosage). [Link] |
| jim2 Member 232 Posts 7/06 | Posted - Nov 10 2013 : 7:42PM Edited by - jim2 on 11/10/2013 7:52:57 PM [Link] |
| BYOB_Kenobi Senior Member “Life can only be understood backwards; but it must be lived forwards.” - Kierkegaard 2684 Posts 8/09 | Posted - Nov 10 2013 : 9:26PM Unfortunately, polypharmacy used to only be seen by geriatric population, but it's getting more common even in young adults or some kids. When you are finding/seeing new doctors (or even with good established long time docs), don't be afraid to say no. They often have the medication/Rx-treatment made up in their minds half way thru the office visit. Don't be afraid to say, "I'm uncomfortable this solution and are their other alternatives?", if you are against the treatment they propose. Also 2nd opinions are always a option. Good luck Jim. Edited by - BYOB_Kenobi on 11/11/2013 10:26:26 PM [Link] |
| mharris127 Senior Member 1844 Posts 8/09 | Posted - Nov 11 2013 : 4:29AM It does make me feel better that you weren't prescribed an antipsychotic for sleep purposes. Kenobi's data concerns me, I had thought this concern was mainly a problem for doctors over 50. Younger doctors taking up the practice as well is concerning. Another issue is the lack of psychiatrists nowadays forcing general practitioners to deal with and prescribe for mental illnesses where they probably weren't specifically trained in them like a psychiatrist would be (I know MDs not specializing in mental illnesses take one or two classes in psychiatry as an overview). [Link] |
| jim2 Member 232 Posts 7/06 | Posted - Nov 11 2013 : 10:12AM [Link] |
| mharris127 Senior Member 1844 Posts 8/09 | Posted - Nov 11 2013 : 12:15PM I am glad you are starting to manage better, hopefully your anxiety level keep improving. If you end up needing benzos for it you could always go to your psychiatrist (or GP) and ask for a 14 pill supply with an agreement that you will only take one as needed, no one gets hooked on 14 pills. The cost would probably be less than your generic prescription co-pay, the common benzos have been on generic for so long that they are dirt cheap. [Link] |
| novadates Member 41 Posts 11/13 | Posted - Nov 19 2013 : 2:00AM [Link] |
| mharris127 Senior Member 1844 Posts 8/09 | Posted - Nov 20 2013 : 2:16AM [Link] |
| Joe Mayo Deactivated User Sure Thing, Joe Mayo. 533 Posts 10/13 | Posted - Nov 20 2013 : 11:58AM You're a fucking douche. Go try to be funny in a thread with a less serious topic. [Link] |
| Cerebral Jedi Senior Member I don't trust men who don't like big tits. 1067 Posts 12/04 | Posted - Nov 21 2013 : 2:05PM [Link] |
| mharris127 Senior Member 1844 Posts 8/09 | Posted - Nov 21 2013 : 5:54PM [Link] |
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