The other white meat of anti-ad and anti-spyware software is SpyBot Search & Destroy. It included a different (although overlapping) set of tools aiding in keeping your computer clean.
Between the two programs and a good anti-virus (Norton or McAfee) program, you shouldn't have much of a problem. I'd suggest that you run each of them weekly.
Other useful aids include the Google toolbar and a utility called PopUp Stopper.
You might also change your cookie settings. I have my computer set to accept first party and session cookies and to ASK for all 3rd party cookies. Then, when the little window opens asking me to accept or reject cookies not directly related to the page I'm on, I use common sense and check to "always" block most of them. It is a nuisance at first but after a couple of weeks, you will have blocked most of the offenders and the interruption will almost go away.
~ GaySatyr

